Biomarkers of Aging Built on Solid Science
An unparalleled and focused array of extensively tested biomarkers shown to highly correlate with age that are both medically and statistically significant.
Detail and precision are crucial differences that set PhysioAge® apart from other health tests.
Our expert system is based on solid science – extensive clinical trials, scientific literature, and careful statistical analysis of primary data. Rather than using secondary clinical studies to calculate physiological age, we used our own in-depth primary research to measure up to 120 attributes in a database of 4,500 individuals. This method determined how biomarkers relate to each other, enabling a greater degree of statistical accuracy and a deeper understanding of the aging process. With unique in-house measurements, PhysioAge® gives you complete, clear, and precise results.
CardioAge®
Arterial Stiffness Testing with SphygmoCor by Atcor Medical
- Measures the suppleness of your arteries using pulse wave analysis
- Assesses cardiovascular risk by measuring augmentation pressure
The gold standard in central blood pressure assessment, the SphygmoCor has been used in more clinical studies than any other device. Central blood pressure has been shown to be a superior predictor of cardiovascular events. In fact, the Mayo Clinic has adopted the SphygmoCor as the standard hypertension screening device.
Functioning essentially like a noninvasive A-line, SphygmoCor CP takes a 10-second snapshot of the radial arterial pressure wave and derives the ascending aortic pressure wave, providing critical cardiovascular measurements including central blood pressure, aortic augmentation index, ejection duration and a subendocardial viability ratio. Our algorithms calculate a CardioAge based on augmentation pressure, the most age-sensitive measurement generated.
CutoAge®
Skin Elasticity Testing with C+K Cutometer
- Assesses the elasticity of the skin with the same instrument used in numerous clinical trials of OTC and pharmaceutical skin care products
- Determines the propensity to develop wrinkles by measuring elasticity, firmness, and resistance to stress
The Cutometer MPA 580 is the gold standard in dermatology to measure elasticity and other biomechanical parameters of the skin. The device uses gentle suction to draw the skin into the aperture of the probe, where penetration depth is determined by an optical measuring system. The resistance of the skin to be sucked up by negative pressure (firmness) and its ability to return into its original position (elasticity) are displayed as curves. Our algorithms calculate a CutoAge based on the most age-sensitive parameters of these curves.
PulmoAge®
Pulmonary Function Testing with EasyOne Air Spirometer from NDD
- Measures forced expiratory volume (FEV1/FCV), which is highly correlated with age
- Predicts all-cause mortality, not just mortality from pulmonary disease
The EasyOne Air digital spirometer is a flexible, accurate and proven spirometry solution designed for healthcare providers large and small. Utilizing TrueFlow™ technology, this portable spirometer delivers reliable results without the need for calibration to ensure lifetime worry-free operation.
Thanks to the vivid color touch screen, it is easy to navigate, view real-time results and enter data. Easily connect to a PC for real-time patient incentives, data exchange and EMR connectivity.
Of the parameters measured by the EasyOne Air Spirometer, FEV1 is the most age-sensitive. Our algorithms calculate a PulmoAge based on FEVI corrected for race, age, sex and height.
NeuroAge®
Cognitive Assessment Testing with CNS Vital Signs
- Measures the most highly age-sensitive aspects of cognitive function using a computerized battery of tests
- Functions as an effective screen for mild cognitive impairment and Alzheimer’s disease
CNS Vital Signs online neurocognitive assessment is a non-invasive clinical procedure to efficiently and objectively assess a broad spectrum of brain function performance or domains under challenge (cognition stress test) to enable the measuring of important clinical symptoms, behaviors, and comorbidities. Of all the parameters measured by CNS Vital Signs, the most age-sensitive are psychomotor speed and processing speed. Our algorithms calculate a NeuroAge using these two parameters.
ImmunoAge®
Immune Function Testing by UCLA School of Medicine
- Measures the health of the immune system using proprietary algorithms of standard immune subsets
- Utilizes cutting-edge molecular markers for senescent and naïve T-cells
TelomerAge®
Telomere Length Measurement by Repeat Diagnostics®
- Measures the ends of the telomeres, the caps at the ends of your chromosomes that act as a molecular clock by shortening with every cell division
- Telomere shortening is highly correlated in numerous studies with aging and many disease states
Reporting
PhysioAge includes an online reporting system that includes a Dashboard, Report Cards, Recommendations, and Reports.
Patient Portal
A dynamic interface for browsing all of your results including biomarkers, labs and any other personalized tests relevant to assessing or monitoring your your health. Accessible from any device.
Report Cards
Our algorithms assign letter grades (A through F) for each result category as well as individual results, in an easy-to-understand format.
Recommendations
Review all of your treatment recommendations in one place.
PDF Reports
Generate several PDF reports of various lengths, from a 2-page digest to a 40-page report with full explanations of each test and what the results mean to you.
Patients gain access to a number of benefits from a PhysioAge® evaluation:
- Benchmark how well your body’s aging
- Track your aging over time
- Identify any organs that need special attention
- Measure the impact of treatments on your health
- Get all your test results in a single interface
- Gain the knowledge you need to be proactive about your health
